Nowadays dealing with R&I implies not only looking after the scientific value of our work but also having clear in mind the effects of what we are doing for society in a wide perspective: from policymakers to enterprises, up to citizens. Research and innovation, therefore, should be able to come out from labs and create bridges with their reference context. To this regard, the challenge is to be able to creating economic, social, cultural and environmental impact looking at them as a measurement of “change”.Through the seminar, we will share and talk about some tools, such as the logical framework matrix, and some concepts, like Responsible Research and Innovation, to comply with this issue.